SALBUTAMOL (US, ALBUTEROL)
sal-byoo-tah-mole / al byoo' ter ole
P - Caution when used during pregnancy
L - Caution when used during lactation
Indication(s) & usage
Salbutamol is indicated for the treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease.
Salbutamol is indicated for the prevention of exercise-induced bronchospasm in patients 4 years of age and older.
Tablet/Syrup: Relief of bronchospasm in bronchial asthma of all types, chronic bronchitis and emphysema.
Dosage & administration
As there may be adverse effects associated with excessive dosing, the dosage or frequency of administration should only be increased on medical advice.
Most common overdose signs and symptoms are transient Beta-agonist pharmacologically mediated events.
History of hypersensitivity to any of the components of Ventolin.
Ampoule: Bronchodilators should not be the only or main treatment in patients with severe or unstable asthma. Severe asthma requires regular medical assessment as death may occur. Patients with severe asthma have constant symptoms and frequent exacerbations, with limited physical capacity and PEF values <60% predicted at baseline with >30% variability, usually not returning entirely to normal after a bronchodilator. These patients will require high dose inhaled (eg, >1 mg/day beclomethasone dipropionate) or oral corticosteroid therapy. Sudden worsening of symptoms may require increased corticosteroid dosage which should be administered under urgent medical supervision.
Adverse Drug Reactions
Immune System Disorders: Very rare: Hypersensitivity reactions including angioedema, urticaria, bronchospasm, hypotension and collapse.
Increased theophylline toxicity with propranolol, cimetidine, erythromycin, quinolone antibiotics. Reduced efficacy with rifampicin, phenobarbitone, phenytoin, carbamazepine, sulfinpyrazone and smoking. Increased risk of hypokalaemia with diuretics. Potentially Fatal: With anaesthetics, pancuronium bromide and sympathomimetics (increased risk of arrhythmias).
Absorption of theophylline reduced variably by different types of food.
Theophylline may cause spurious elevations of serum uric acid and increase in urinary catecholamines.
Tablet: Store below 25°C.
Pharmacology: Pharmacodynamics: Salbutamol is a selective Beta2-adrenoceptor agonist. At therapeutic doses, it acts on the Beta2-adrenoreceptors of bronchial muscle, with little or no action on the Beta1-adrenoreceptors of cardiac muscle.
R03AC02 - salbutamol; Belongs to the class of adrenergic inhalants, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases. R03CC02 - salbutamol; Belongs to the class of adrenergics for systemic use, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases. R03DA04 - theophylline; Belongs to the class of other systemic drugs used in the treatment of obstructive airway diseases, xanthines.
|Brand Name||Manufacturer/Marketer||Composition||Dosage Form||Pack Size & Price|
|ACTOLIN||Globe Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 15.00 MRP|
|ALVOLEX||Silva Pharmaceuticals Limited||Salbutamol 2mg/5ml||Syrup||100ml: 16.07 MRP|
|ASMALIN HFA||Aristopharma Ltd.||Salbutamol 100mcg/puff||Inhaler (MDI)||200 MDI: 175.00 MRP|
|ASMALIN HFA (Refill)||Aristopharma Ltd.||Salbutamol 100mcg/puff||Inhaler (Refill Can)||200 doses canister: 155.00 MRP|
|ASMATOL||Rephco Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||60ml: 14.45 MRP|
|ASMOLEX||Aristopharma Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.92 MRP|
|ASNIL||Ziska Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 16.00 MRP|
|ASTHMOLIN||Pharmadesh Laboratories Limited||Salbutamol 2mg||Tablet||100's: 28.00 MRP|
|ASTHMOLIN Syrup||Pharmadesh Laboratories Limited||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 11.38 & 21.08 MRP|
|ASUL||Asiatic Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.92 MRP|
|AZMAREL||Euro Pharma Ltd.||Salbutamol 2mg & 4mg||Tablet||100's each: 26.00 & 34.00 MRP|
|AZMAREL Syrup||Euro Pharma Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.00 MRP|
|AZMASOL 2||Beximco Pharmaceuticals Ltd||Salbutamol Sulphate BP eq. to 2mg Salbutamol||Tablet||500's: 130.00 MRP|
|AZMASOL 200 REFILL||Beximco Pharmaceuticals Ltd||Salbutamol 100mcg/puff||Inhaler Refill||200MD: 150.00 MRP|
|AZMASOL 4||Beximco Pharmaceuticals Ltd||Salbutamol Sulphate BP eq. to 4mg Salbutamol||Tablet||500's: 200.00 MRP|
|AZMASOL BEXICAP||Beximco Pharmaceuticals Ltd||Salbutamol 0.20mg||Capsule||30's: 75.00 MRP|
|AZMASOL HFA 200||Beximco Pharmaceuticals Ltd||Salbutamol 100mcg/puff||Inhaler||200MD: 180.00 MRP|
|AZMASOL HFA 300||Beximco Pharmaceuticals Ltd||Salbutamol 100mcg/puff||Inhaler||300MD: 260.00 MRP|
|AZMASOL SOLUTION||Beximco Pharmaceuticals Ltd||Salbutamol Sulphate 5mg/ml (i.e.0.5%)||Solution||20ml: 120.00 MRP|
|AZMET||Medicon Laboratories Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 15.00 & 22.00 MRP|
|BROAD||Nipa Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 15.00 MRP|
|BRODIL||ACI Ltd.||Salbutamol 2mg & 4mg||Tablet||500's each: 130.00 & 200.00 MRP|
|BRODIL HFA||ACI Ltd.||Salbutamol 100mcg/puff||Inhaler (MDI)||200 MDI: 175.66 MRP|
|BRODIL HFA (Refill)||ACI Ltd.||Salbutamol 100mcg/puff||Inhaler (Refill Can)||200 doses can: 155.58 MRP|
|BRODIL Inhaler||ACI Ltd.||Salbutamol 100mcg/puff||Inhaler (MDI)||200 MDI: 160.00 MRP|
|BRODIL Syrup||ACI Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.93 MRP|
|BROLAX||Somatec Pharmaceuticals Ltd.||Salbutamol 2mg & 4mg||Tablet||400's each: 25.00 & 33.00 MRP|
|BROLAX Syrup||Somatec Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 15.06 MRP|
|BRONCOTROL||Pacific Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 16.11 MRP|
|BRONCOTROL 4||Pacific Pharmaceuticals Ltd.||Salbutamol 4mg||Tablet||200's: 68.00 MRP|
|BRONDYL||Millat Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 22.80 MRP|
|BRONIL-S||Seema Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.00 MRP|
|BRONKOLAX||Beximco Pharmaceuticals Ltd||Salbutamol Sulphate BP eq. to Salbutamol 2mg/5ml||Syrup||100ml: 22.93 MRP|
|D-BUTAMOL||Doctors Chemical Works Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 22.80 MRP|
|DECABUTAMOL||Decent Pharma Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 12.00 & 21.83 MRP|
|DILATOL||Kemiko Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 22.84 MRP|
|ETOL||Edruc Limited||Salbutamol 2mg/5ml||Syrup||100ml: 22.00 MRP|
|G-SALBUTAMOL||Gonoshasthaya Pharmaceuticals Ltd||Salbutamol 4mg||Tablet||100's: 35.00 MRP|
|G-SALBUTAMOL Injection||Gonoshasthaya Pharmaceuticals Ltd||Salbutamol 50mcg||Injection||20ml vial: 101.53 MRP|
|G-SALBUTAMOL Syrup||Gonoshasthaya Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 15.05 MRP|
|H-SELAX||Hudson Pharmaceuticals Ltd||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|H-SELAX Syrup||Hudson Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 10.80 & 15.00 MRP|
|ORSAL||Orion Pharma Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.85 MRP|
|PULMOLIN||Opsonin Pharma Limited||Salbutamol 4mg||Tablet||100's: 33.00 MRP|
|PULMOLIN Syrup||Opsonin Pharma Limited||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 10.45 & 22.85 MRP|
|RESDIL||Cosmo Pharma Laboratories Ltd.||Salbutamol 4mg||Tablet||200's: 66.00 MRP|
|RESPOLIN||Jayson Pharmaceuticals Ltd.||Salbutamol 4mg||Tablet||100's: 25.00 MRP|
|RESPOLIN Syrup||Jayson Pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.92 MRP|
|SABUL||Chemist Laboratories Ltd.||Salbutamol sulphate 5mg/ml||Nebuliser Solution||20ml: 110.00 MRP|
|SALBU||Biopharma Laboratories Ltd||Salbutamol 2mg & 4mg||Tablet||100's each: 26.00 & 34.00 MRP|
|SALBU Syrup||Biopharma Laboratories Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 11.04 & 22.93 MRP|
|SALBUMOL||Indo-Bangla Pharmaceuticals Works Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 16.00 MRP|
|SALBUT||General Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 22.90 MRP|
|SALBUTAL||Sanofi||Salbutamol 2mg & 4mg||Tablet||500's each: 130.01 & 169.97 MRP|
|SALBUTAL Syrup||Sanofi||Salbutamol 2mg/5ml||Syrup||100ml: 22.89 MRP|
|SALBUTAMOL||Bristol Pharma Limited||Salbutamol 2mg & 4mg||Tablet||500's each: 130.00 & 170.00 MRP|
|SALBUTAMOL Syrup||Amico Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 21.75 MRP|
|SALIX||Modern Pharmaceuticals Ltd||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|SALIX-4||Modern Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 10.80 & 22.90 MRP|
|SALMOL||Medimet Pharmaceuticals Ltd||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|SALMOL Syrup||Medimet Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 13.00 & 20.00 MRP|
|SALMOLIN||The Acme Laboratories Ltd.||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|SALMOLIN 200||The Acme Laboratories Ltd.||Salbutamol 200mcg/rotacap||Inhaler (DPI)||30 & 100 caps: 37.50 & 125.00 MRP|
|SALMOLIN Inhaler||The Acme Laboratories Ltd.||Salbutamol 100mcg/puff||Inhaler (MDI)||200 MDI: 180.68 MRP|
|SALMOLIN Resp Soln||The Acme Laboratories Ltd.||Salbutamol sulphate 5mg/ml||Inhalation Solution||20ml: 120.00 MRP|
|SALMOLIN Syrup||The Acme Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 10.83 & 22.93 MRP|
|SALOL||Cosmic Chemical Industries Limited||Salbutamol 2mg/5ml||Syrup||100ml: 22.00 MRP|
|SALOMAX 100||Eskayef Bangladesh Ltd||Salbutamol 100mcg/puff, 200MD||Inhaler (MDI)||200 MDI, MRP: 160.00|
|SULBLON||Kumudini Pharma Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 22.00 MRP|
|SULTOLIN 4||Square Pharmaceuticals Ltd.||Salbutamol 4mg||Tablet||20x10's: 92.00 MRP|
|SULTOLIN COZYCAP||Square Pharmaceuticals Ltd.||Salbutamol 200 mcg||Cozycap||5x6's: 75.30 MRP|
|SULTOLIN HFA||Square Pharmaceuticals Ltd.||Salbutamol 100 mcg/puff||HFA Inhaler (CFC-Free)||200 puffs: 195.59 MRP|
|SULTOLIN HFA REFILL||Square Pharmaceuticals Ltd.||Salbutamol 100 mcg/puff||HFA Refill (CFC-Free)||200 puffs: 170.51 MRP|
|SULTOLIN RESP||Square Pharmaceuticals Ltd.||Salbutamol 5mg/ml||Respirator Solution||20 ml: 120.82 MRP|
|SULTOLIN SR-TAB||Square Pharmaceuticals Ltd.||Salbutamol 8mg||Tablet||20x10's: 184.00 MRP|
|SULTOLIN SYP||Square Pharmaceuticals Ltd.||Salbutamol 2mg/5 ml||Syrup||100 ml: 23.00 MRP|
|TOLIN||Mystic Pharmaceuticals Limited||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|TOLIN Syrup||Mystic Pharmaceuticals Limited||Salbutamol 2mg/5ml||Syrup||100ml: 15.00 MRP|
|VENLET||Apollo Pharmaceutical Laboratories Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 15.00 MRP|
|VENTISAL||IBN SINA Pharmaceutical Industry Ltd.||Salbutamol 4mg||Tablet||100's: 34.00 MRP|
|VENTISAL Syrup||IBN SINA Pharmaceutical Industry Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 22.92 MRP|
|VENTOL CPL||Central Pharmaceuticals Ltd||Salbutamol 2mg/5ml||Syrup||60ml, 100ml: 10.50 & 15.00 MRP|
|VENTOL Syrup||Gaco Pharmaceutical Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 10.50 MRP|
|VENTOLEX||Desh Pharmaceuticals (Pvt) Ltd||Salbutamol 2mg/5ml||Syrup||100ml: 16.00 MRP|
|VENTOLEX-4||Desh Pharmaceuticals (Pvt) Ltd||Salbutamol 4mg||Tablet||500's: 170.00 MRP|
|VENTOLIN||GlaxoSmithKline Bangladesh Limited||Salbutamol 2mg & 4mg||Tablet||500's each: 131.67 & 172.23 MRP|
|VENTOLIN HFA||GlaxoSmithKline Bangladesh Limited||Salbutamol 100mcg/puff||Evohaler (MDI)||200 MDI: 200.00 MRP|
|VENTOLIN Nebuliser Soln||GlaxoSmithKline Bangladesh Limited||Salbutamol sulphate 2.5mg/2.5ml||Nebuliser Solution||2.5ml x30's: 803.40 MRP|
|VENTOLIN Resp Soln||GlaxoSmithKline Bangladesh Limited||Salbutamol sulphate 5mg/ml||Inhalation Solution||20ml: 172.90 MRP|
|VENTOLIN Syrup||GlaxoSmithKline Bangladesh Limited||Salbutamol 2mg/5ml||Syrup||100ml: 22.93 MRP|
|VENTOLIN-SR||GlaxoSmithKline Bangladesh Limited||Salbutamol 8mg||Tablet (sustained release)||250's: 194.84 MRP|
|VENTOSOL||Ad-din pharmaceuticals Ltd.||Salbutamol 2mg/5ml||Syrup||100ml: 20.00 MRP|
|Windel 2||Incepta Pharmaceuticals Limited||Salbutamol Sulphate BP equivalent to 2mg Salbutamol||Tablet||20x10's:MRP 52 Tk|
|Windel 4||Incepta Pharmaceuticals Limited||Salbutamol Sulphate BP equivalent to 4mg Salbutamol||Tablet||20x10's:MRP 68 Tk|
|Windel Nebuliser Soln||Incepta Pharmaceuticals Limited||Salbutamol Sulphate BP equivalent to Salbutamol 2.5mg/2.5ml||Nebuliser solution||10x1's:MRP 140 Tk|
|WINDEL Resp Soln||Incepta Pharmaceuticals Limited||Salbutamol Sulphate BP equivalent to Sulbutamol 5mg/ml||Inhalation Solution||1's: 120.00 MRP|
|Windel Syrup||Incepta Pharmaceuticals Limited||Salbutamol Sulphate BP equivalent to Salbutamol 2mg/5ml||Syrup||100ml:MRP 22.9 Tk|
|ZENTOLIN||Zenith Pharmaceuticals Ltd.||Salbutamol sulphate 2mg/5ml||Syrup||60ml, 100ml: 10.00 & 15.60 MRP|
Why this medication is prescribed?
Salbutamol/Albuterol is used to prevent and treat wheezing, difficulty breathing, chest tightness, and coughing caused by lung diseases such as asthma and chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways). Salbutamol/Albuterol is in a class of medications called bronchodilators. It works by relaxing and opening the air passages to the lungs to make breathing easier.
How to use this medicine?
Salbutamol (Albuterol) may come as a tablet, a syrup and an extended-release (long-acting) tablet to take by mouth as well as Inhaler or Respiratory Solution. The tablets and syrup are usually taken three or four times a day. The extended-release tablets are usually taken once every 12 hours. Take albuterol at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Salbutamol (Albuterol) exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the extended-release tablets whole with plenty of water or other liquid. Do not split, chew, or crush them. Your doctor may start you on a low dose of Salbutamol (Albuterol) and gradually increase your dose.
Salbutamol (Albuterol) may help control your symptoms but will not cure your condition. Continue to take Salbutamol (Albuterol) even if you feel well. Do not stop taking Salbutamol (Albuterol) without talking to your doctor.
Call your doctor if your symptoms worsen or if you feel that Salbutamol (Albuterol) no longer controls your symptoms.
This medication may be prescribed for other uses; ask your doctor for more information.
What special precautions to follow?
Before taking Salbutamol (Albuterol),
- tell your doctor if you are allergic to Salbutamol (Albuterol), any other medications, or any of the ingredients in Salbutamol (Albuterol) tablets, extended-release tablets, or capsules.
- tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: beta blockers such as atenolol, labetalol, metoprolol, nadolol, and propranolol; digoxin; diuretics ('water pills'); epinephrine; other oral and inhaled medications for asthma and medications for colds. Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine (Tofranil), nortriptyline, protriptyline, and trimipramine; and monoamine oxidase (MAO) inhibitors, including isocarboxazid, phenelzine, selegiline, and tranylcypromine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had an irregular heartbeat, heart disease, high blood pressure, hyperthyroidism (condition in which there is too much thyroid hormone in the body), diabetes, or seizures.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Salbutamol (Albuterol), call your doctor.
- you should know that Salbutamol (Albuterol) sometimes causes wheezing and difficulty breathing. If this happens, call your doctor right away. Do not use Salbutamol (Albuterol) again unless your doctor tells you that you should.
What special dietary instructions to follow?
Unless your doctor tells you otherwise, continue your normal diet.
What to do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Salbutamol (Albuterol) may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- uncontrollable shaking of a part of the body
- muscle cramps
- excessive motion or activity
- sudden changes in mood
- increased or decreased appetite
- difficulty falling asleep or staying asleep
- pale skin
- Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- fast, pounding, or irregular heartbeat
- chest pain
- blisters or rash
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- increased difficulty breathing
- difficulty swallowing
Salbutamol (Albuterol) may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What other information to know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.
Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Ref: U.S. Natl. Library of Medicine
This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.