(pan cree ah tin)
P : Caution when used during pregnancy
L : Caution when used during lactation
|| See TERMINOLOGY & ABBREVIATIONS ||
|Indication(s) & Dosage||Pancreatic insufficiency
Adult: Dose is adjusted according to dosage form and patient's needs. Usual dose with each meal: 5,000-56,000 units of lipase activity (with varying proportions of protease and amylase activity, depending on the preparation).
Child: Dose dependant upon dosage form and patient's needs. Children with cystic fibrosis max dose: 10,000 units lipase/kg/day.
|Administration||May be taken with or without food.
|Overdosage||May lead to laxative effect; treatment: supportive.|
|Contraindications||Acute pancreatitis or acute exacerbation of chronic pancreatic disease.|
|Special Precautions||Avoid high doses in patients with cystic fibrosis. Maintain adequate hydration. Some products contain pork protein. Inactivated by heat; do not mix with hot food or liquids. May irritate oral mucosa; should not be held in mouth. Pregnancy and lactation.|
|Adverse Drug Reaction(s)||GI effects e.g. abdominal discomfort, nausea and vomiting. Buccal and perianal irritation, particularly in infants. Colonic strictures may occur, mainly in children with cystic fibrosis receiving high doses of pancreatin preparations. Hyperuricaemia and hyperuricosuria may occur.|
|Drug Interactions||May impair the oral absorption of folic acid when taken together; antagonises hypoglycaemic effect of acarbose.
|Storage||Store at 15-30Â°C. Protect from humidity.|
|Pharmacology||Pancreatin are pancreatic enzymes which hydrolyse fats to glycerol and fatty acids, break down protein into peptides, proteoses and derived substances, and convert starch into dextrins and sugars.|
Search Google: Pancreatin
|Brand Name||Manufacturer/Marketer||Composition||Dosage Form||Pack Size & Price|
|A-ZYME||The Acme Laboratories Ltd.||Pancreatin 325mg||Tablet (enteric coated)||100's: 173.00 MRP|
|CREZYME||Opsonin Pharma Limited||Pancreatin 325mg||Tablet (enteric coated)||100's: 120.00 MRP|
|SUZYME 325||Square Pharmaceuticals Ltd.||Pancreatin 325mg||Tablet||10x10's: 351.00 MRP|
|ZYMET||Beximco Pharmaceuticals Ltd||Pancreatin BP 325mg||Tablet (Sugar & Ent. Coated)||100's: 300.00 MRP|