Beclomethasone (Beclometasone)

(be kloe meth' a sone)

PCaution when used during lactation  - Caution when used during pregnancy

LCaution when used during lactation  - Caution when used during lactation

Molecule Info

 
Indication & Dosage Nasal
Treatment and prophylaxis of allergic and non allergic rhinitis
Adult: 100 mcg bid or 50 mcg 3-4 times daily in each nostril. Max: 400 mcg daily.
Inhalation
Asthma prophylaxis
Adult: Initially, 600-800 mcg daily. Maintenance: 400 mcg daily in 2-4 divided doses.
Child: As dipropionate: 50 or 100 mcg bid-qid or 100 or 200 mcg bid.
Inhalation
Severe asthma
Adult: 250 mcg four times daily or 500 mcg bid. May be increased to 500 mcg 3-4 times daily if necessary. Max: 2 mg daily. 
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: Apply a 0.025% cream/ointment onto affected area.

Special Populations: Switch from oral to inhalation steroid for stable asthmatics. Initially, the inhalation is added to existing oral steroid dosage. After 1 wk, oral dose is reduced by 2.5 mg prednisone or its equivalent. Similar reduction is made at wkly intervals depending on patient response. Reinstatement of oral steroid may be needed in times of stress or exacerbation of asthma. Inhalation of beta agonists should be done 5 min before the steroids.
Contraindications Hypersensitivity. Acute infections uncontrolled by antimicrobial chemotherapy.
Special Precautions Active or doubtfully quiescent tuberculosis, paradoxical bronchospasm; children, elderly; pregnancy and lactation.
Adverse Drug Reactions Loss of skin collagen and SC atrophy; local hypopigmentation of deeply pigmented skin; dryness, irritation, epistaxis, rarely ulceration or perforation of the nasal septum; smell and taste disturbances; hoarseness and candidiasis of the mouth or throat.
Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Storage Inhalation: Store at 15-30°C. Nasal: Store at 15-30°C. Topical/Cutaneous:Store at 15-30°C.
Pharmacology Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.
Absorption: Readily absorbed after local application.
Distribution: Rapidly distributed to all body tissues.
Metabolism: Mainly hepatic but also in other tissues including GI tract and lungs.
Excretion: Chiefly in the urine and as metabolites in the faeces.
ATC Classification A07EA07 - beclometasone ; Belongs to the class of corticosteroids acting locally. Used in the treatment of intestinal inflammation. 
R03BA01 - beclometasone ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticooids. 
D07AC15 - beclometasone ; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases. 
R01AD01 - beclometasone ; Belongs to the class of topical corticosteroids used as nasal decongestants.
 

Brand/Product Info


Total Products : 13             
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ASCON The Acme Laboratories Ltd. Beclomethasone dipropionate 100mcg & 250mcg/puff or actuation Inhaler (MDI) 200 MDI each: 200.75 & 250.94 MRP
BECLOCORT HFA Aristopharma Ltd. Beclomethasone dipropionate 50mcg & 100mcg & 250mcg/puff or actuation Inhaler (MDI) 200 MDI each: 220.00 & 270.00 & 350.00 MRP
BECLOD The Acme Laboratories Ltd. Beclomethasone dipropionate 100mcg+200mcg/puff Inhaler (DPI) 30 doses (rotacap) each: 45.00 & 63.90 MRP
BECLOMIN 100 Square Pharmaceuticals Ltd. Beclometasone 100 mcg/puff HFA Inhaler (CFC-Free) 200 puffs: 270.82 MRP
BECLOMIN 250 Square Pharmaceuticals Ltd. Beclometasone 250 mcg/puff HFA Inhaler (CFC-Free) 200 puffs: 320.96 MRP
BECONASE Aq GlaxoSmithKline Bangladesh Limited Beclomethasone dipropionate 50mcg/metered dose MD Spray 200 dose spray unit: 235.54 MRP
BECOSPRAY N-SPRAY Square Pharmaceuticals Ltd. Beclomethasone 50 mcg/spray Nasal Spray 200 sprays: 125.85 MRP
DECOMIT 100 Beximco Pharmaceuticals Ltd Beclomethasne dipropionate 100mcg/puff HFA Inhaler 200MD: 270.00 MRP
DECOMIT 100 Inhaler Beximco Pharmaceuticals Ltd Beclomethasne dipropionate HFA Inhaler 200MD: 200.00 MRP
DECOMIT 250 Inhaler Beximco Pharmaceuticals Ltd Beclomethason dipropionate HFA Inhaler 200MD: 250.00 MRP
DECOMIT 50 Beximco Pharmaceuticals Ltd Beclomethason dipropionate 50mcg/puff HFA Inhaler 200MD: 220.00 MRP
DECOMIT N Beximco Pharmaceuticals Ltd Beclomethasone dipropionate Spray 200MD: 146.00 MRP
STERADIN HFA ACI Ltd. Beclomethasone dipropionate 50mcg & 100mcg/puff Inhaler (MDI) 200 MDI each: 271.02 & 351.32 MRP

Gen. MedInfo

IMPORTANT WARNING:

If you are switching (or have recently switched) to beclomethasone inhalation from an oral corticosteroid such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), or prednisone (Deltasone) and have an injury, infection, severe asthma attack, or surgery, use a full dose of oral corticosteroid (even if you have been gradually decreasing your dose) and call your doctor for additional instructions.

Carry an identification card saying that you may need to use extra doses of the corticosteroid during times of stress (injuries, infections, and severe asthma attacks). Write down the name of the medication and the full dose you took before decreasing it. Ask your pharmacist or doctor how to get this card. List your name, medical problems, medications and dosages, and doctor's name and telephone number on the card.

 

Why is this medication prescribed?

Beclomethasone is used to prevent wheezing, shortness of breath, coughing, and chest tightness caused by severe asthma and other lung diseases. Beclomethasone is in a class of medications called corticosteroids. It works by reducing swelling in the airways. It is also used to prevent allergy symptoms including sneezing, itching, runny or stuffed nose and to shrink nasal polyps (lumps) and prevent them from returning after surgical removal.

How should this medicine be used?

Beclomethasone comes as an aerosol to inhale by mouth, as an aerosol and a solution to inhale through the nose. It usually is inhaled two or four times a day at evenly spaced intervals. Follow the directions on your prescription label carefully, and ask your doctor to explain any part you do not understand. Use beclomethasone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

If your doctor has prescribed a bronchodilator (a drug to be inhaled for rapid relief of difficult breathing), use it several minutes before your beclomethasone inhaler so that beclomethasone reaches deep into your lungs.

Beclomethasone controls symptoms of asthma and other lung diseases but does not cure them. Continue to use beclomethasone even if you feel well. Do not stop using beclomethasone without talking to your doctor.

Before you use beclomethasone the first time, read the written instructions that come with it. Ask your doctor, pharmacist, or respiratory therapist to show you how to use it. Practice using the inhaler while he or she watches.

To use the inhaler, follow these steps: If you have difficulty getting the medication into your lungs, a spacer (a special device that attaches to the inhaler) may help; ask your doctor, pharmacist, or respiratory therapist.

  1. Shake the inhaler well. (Note: If you are using QVAR, you do not need to shake the inhaler.)

  2. Remove the protective cap.

  3. Exhale (breathe out) as completely as possible through your nose while keeping your mouth shut.

  4. Open Mouth Technique: Open your mouth wide, and place the open end of the mouthpiece about 1-2 inches from your mouth.

    Closed Mouth Technique: Place the open end of the mouthpiece well into your mouth, past your front teeth. Close your lips tightly around the mouthpiece.

  5. Take a slow, deep breath through the mouthpiece and, at the same time, press down on the container to spray the medication into your mouth. Be sure that the mist goes into your throat and is not blocked by your teeth or tongue. Adults giving the treatment to young children may hold the child's nose closed to be sure that the medication goes into the child's throat.

  6. Hold your breath for 5-10 seconds, remove the inhaler, and exhale slowly through your nose or mouth. If you take two puffs, wait 2 minutes and shake the inhaler well before taking the second puff.

  7. Replace the protective cap on the inhaler.

  8. After each treatment, rinse your mouth with water or mouthwash.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor for more information.
 
What special precautions should I follow?
 
Before using beclomethasone,
  • tell your doctor if you are allergic to beclomethasone or any other drugs.
  • tell your doctor what prescription and nonprescription medications you are taking, especially arthritis medications, aspirin, digoxin, diuretics (water pills), estrogen, ketoconazole, oral contraceptives, phenobarbital, phenytoin, rifampin, theophylline, and vitamins.
  • if you have a fungal infection (other than on your skin), do not use beclomethasone without talking to your doctor.
  • tell your doctor if you have or have ever had liver, kidney, intestinal, or heart disease; diabetes; an underactive thyroid gland; high blood pressure; mental illness; myasthenia gravis; osteoporosis; herpes eye infection; seizures; or ulcers.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using beclomethasone, call your doctor.
  • if you have a history of ulcers or use large doses of aspirin or other arthritis medication, limit your consumption of alcoholic beverages while using this drug. Beclomethasone makes your stomach and intestines more susceptible to the irritating effects of alcohol, aspirin, and certain arthritis medications; this effect increases your risk of getting ulcers.
  • do not use beclomethasone during a sudden asthma attack. You should have a fast-acting inhaler such as salbutamol/albuterol (Ventolin) to use during asthma attacks.
  • avoid exposure to chicken pox and measles. This drug makes you more likely to catch these illnesses. If you are exposed to them while using beclomethasone, call your doctor. Do not have a vaccination or other immunization without your doctor's approval.

What special dietary instructions should I follow?

Your doctor may tell you to follow a low-sodium, low-salt, potassium-rich, or high-protein diet. Follow these directions.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
 
What side effects can this medication cause?
 
Beclomethasone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • dry or irritated throat and mouth

  • cough

  • difficult or painful speech

If you experience any of the following symptoms, call your doctor immediately:

  • skin rash

  • increased difficulty breathing

  • white spots or sores in your mouth

  • swollen face, lower legs, or ankles

  • vision problems

  • cold or infection that lasts a long time

  • muscle weakness

This medication may cause other side effects.  Consult your doctor if you have any unusual problems while taking this.

What other information should I know?

Keep all appointments with your doctor and the laboratory.

Report any injuries or signs of infection (fever, sore throat, pain during urination, and muscle aches) that occur during treatment.

If the sputum (spit) you cough up during an asthma attack thickens or changes color from clear white to yellow, green, or gray, call your doctor; these changes may be signs of an infection.

Inhalation devices require regular cleaning. Once a week, remove the drug container from the plastic mouthpiece, wash the mouthpiece with warm tap water, and dry it thoroughly.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

 

 


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.