P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

Indication & Dosage Nasal
Nasal congestion
Adult: As 0.1% solution: Instill into each nostril bid-tid. Max duration: 7 days. 
Child: As 0.05% solution: 3 mth-12 yr: 1-2 drops into each nostril once or bid. Max duration: 7 days. 
Conjunctival decongestant
Adult: As 0.05-0.1% solution: Instil into the eye.
Contraindications Angle closure glaucoma; dry rhinitis; post trans-sphenoidal hypophysectomy, trans-nasal, trans-oral surgery where dura mater is exposed.
Special Precautions Young children, pregnancy and lactation. Hypertension, CV abnormalities, DM, hyperthyroidism, history of excessive reaction to sympathomimetics, difficulty in urination secondary to prostate enlargement. Rebound congestion may occur after prolonged regular use.
Adverse Drug Reactions Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Nasal drops: Local stinging or burning, sneezing, dryness of mouth and throat, nausea. Eye drops: Dryness of eye.
Drug Interactions Increased heart rate or BP with sibutramine.
Potentially Fatal: Hypertensive crisis with MAOIs. Please consult detailed drug interactions before prescribing.
Storage Nasal: Store below 30°C. Ophthalmic: Store below 30°C.
Pharmacology Xylometazoline is a direct-acting sympathomimetic which has a vasoconstrictor effect by reducing swelling and congestion when applied to mucous membranes.
Onset: 5-10 min.
Duration: 10 hr.
ATC Classification S01GA03 - xylometazoline ; Belongs to the class of sympathomimetics used as ophthalmologic decongestants. 
R01AA07 - xylometazoline ; Belongs to the class of topical sympathomimetic agents used as nasal decongestants. 
R01AB06 - xylometazoline ; Belongs to the class of topical sympathomimetic combination preparations, excluding corticosteroids. Used as nasal decongestants.

Brand/Product Info

Total Products : 6      
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ANTAZOL 0.05% Square Pharmaceuticals Ltd. Xylometazoline 0.05% Nasal Drops 12's: 132.48 MRP
ANTAZOL 0.10% Square Pharmaceuticals Ltd. Xylometazoline 0.1% Nasal Drops 12's: 138.60 MRP
NOVIN Gaco Pharmaceutical Ltd. Xylometazoline hydrochloride 0.05% & 0.10% Nasal Drop 10ml each: 6.89 & 7.50 MRP
RHINOZOL The Acme Laboratories Ltd. Xylometazoline hydrochloride 0.05% & 0.10% Nasal Drop 15ml each: 6.99 & 7.62 MRP
XYLOMET Opsonin Pharma Limited Xylometazoline hydrochloride 0.1% Nasal Drop 10ml: 7.62 MRP
XYLOVIN Opso Saline Ltd. Xylometazoline hydrochloride 0.05% & 0.10% Nasal Drop 10ml each: 7.28 & 7.28 MRP