mph Bangladesh


Olopatadine

(oh loe pa ta' deen)

P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

 
Indication & Dosage Nasal
Allergic rhinitis
Adult: ≥12 yr: As 0.6% nasal spray: Instill 2 sprays into each nostril twice daily.
Ophthalmic
Allergic conjunctivitis
Adult: As 0.1% solution: 1 or 2 drops in the affected eye(s) bid at an interval of 6-8 hr. Alternatively, as a 0.2% solution: 1 drop in the affected eye(s) once daily.
Child: ≥3 yr: As 0.1% solution: 1 or 2 drops in the affected eye(s) bid at an interval of 6-8 hr. Alternatively, as a 0.2% solution: 1 drop in the affected eye(s) once daily.
Contraindications Hypersensitivity. Ophthalmic: Children <3 yr. Nasal: Children <12 yr.
Special Precautions Pregnancy, lactation. Ophthalmic: Remove contact lenses prior to eye admin. Reinsert soft contact lenses 10 min after admin.
Adverse Drug Reactions Ophthalmic: Headache; asthenia; cold syndrome; pharyngitis; rhinitis; sinusitis; dysgeusia; ocular burning or stinging; dry eye; foreign body sensation; hyperaemia; keratitis; lid oedema; ocular pruritus; blurred vision. Nasal: Bitter taste, nasal ulceration, epistaxis, drowsiness.
Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Storage Nasal: Store at 4 to 25 °C. Ophthalmic: Store at 2-25°C.
Pharmacology Olopatadine is a relatively selective histamine H1-receptor antagonist and inhibits the release of histamine from mast cells. It shares many of the pharmacologic effects of mast cell stabilisers.
Absorption: Ophthalmic: Little systemic absorption.
Distribution: Protein-binding: 55%
Metabolism: Not extensively metabolised.
Excretion: Via urine: 60-70 %, via faeces: 17 %
ATC Classification S01GX09 - olopatadine; Belongs to the class of other agent used as ophthalmologic antiallergics. 
R01AC08 - olopatadine.

Brand/Product Info


Total Products : 18                  
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ADIN DS Aristopharma Ltd. Olopatadine hydrochloride INN 2mg/ml (0.2%) Eye Drop 5ml: 150.00 MRP
ALACOT 0.10% Square Pharmaceuticals Ltd. Olopatadine 0.1% Eye Drops 5 ml: 110.34 MRP
ALACOT DS Square Pharmaceuticals Ltd. Olopatadine 0.2% Eye Drops 5 ml: 150.45 MRP
ALCHEK Apex Pharmaceuticals Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.00 MRP
ALERCON The Acme Laboratories Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.00 MRP
CONTOVA ACI Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.38 MRP
Lopadine DS Incepta Pharmaceuticals Limited Olopatadine 0.2% Eye Drops Eye Drop 5ml:MRP 150 Tk
Lopadine Eye Incepta Pharmaceuticals Limited Olopatadine 0.1% Eye Drops Drop 5ml:MRP 110 Tk
Lopadine Nasal Incepta Pharmaceuticals Limited Olopatadine 0.6% Nasal Spray Nasal Spray 120 Metered Dose:MRP 400 Tk
OLODIN Reman Drug Laboratories Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.38 MRP
OLOPAN DROP Beximco Pharmaceuticals Ltd Olopatadine Hydrochloride INN eq. To Olopatadine 1mg/ml Drop 5ml: 100.00 MRP
OLOPAN DS Beximco Pharmaceuticals Ltd Olopatadine Hydrochloride INN eq. To Olopatadine 2mg/ml Solution 5ml: 150.00 MRP
OLOPAN SPRAY Beximco Pharmaceuticals Ltd Olopatadin 0.6gm/100ml, 120 Metered Spray Nasal Spray 1's: 400.00 MRP
OLPADIN Aristopharma Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.00 MRP
PATADIN Popular Pharmaceuticals Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 100.38 MRP
PATADIN DS Popular Pharmaceuticals Ltd. Olopatadine hydrochloride INN 2mg/ml (0.2%) Eye Drop 5ml: 150.57 MRP
PATALOIN IBN SINA Pharmaceutical Industry Ltd. Olopatadine hydrochloride INN 1mg/ml (0.1%) Eye Drop 5ml: 110.00 MRP
PATALON DS IBN SINA Pharmaceutical Industry Ltd. Olopatadine hydrochloride INN 2mg/ml (0.2%) Eye Drop 5ml: 150.00 MRP

Gen. MedInfo

Why is this medication prescribed?

Ophthlamic olopatadine is used to treat the symptoms of allergic pink eye. Olopatadine is in a class of medications called antihistamines. It works by blocking histamine, a substance in the body that causes allergic symptoms.

How should this medicine be used?

Ophthlamic olopatadine comes as a solution (liquid) to instill in the eye. It is usually instilled in the affected eye(s) twice a day, around 6 to 8 hours apart. To help you remember to use olopatadine, use it around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use olopatadine exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

To instill the eye drops, follow these steps: 

  1. Wash your hands thoroughly with soap and water.

  2. Check the dropper tip to make sure that it is not chipped or cracked.

  3. Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.

  4. While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.

  5. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.

  6. Brace the remaining fingers of that hand against your face.

  7. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.

  8. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.

  9. Place a finger on the tear duct and apply gentle pressure.

  10. Wipe any excess liquid from your face with a tissue.

  11. If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.

  12. Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.

  13. Wash your hands to remove any medication.

Other uses for this medicine

This medication may be prescribed for other uses like nasal Allergic Rhinitis; ask your doctor for more information.

What special precautions should I follow?

Before using olopatadine eye drops, 

  • tell your doctor if you are allergic to olopatadine, benzalkonium chloride, or any other medications.
  • tell your doctor what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using olopatadine, call your doctor.
  • you should know that you should not wear contact lenses if your eye(s) is/are red. If your eye is not red and you wear contact lenses, you should know that olopatadine solution contains benzalkonium chloride, which can be absorbed by soft contact lenses. Remove your contact lenses before applying olopatadine and put them back in 10 minutes later.

What special dietary instructions should I follow? 

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Instill the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

What side effects can this medication cause?

Olopatadine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache

  • blurred vision

  • eye burning or stinging

  • dry eyes

  • sore throat

  • taste changes

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to this medicine.

Do not let anyone else use your medication. If you still have symptoms and need further treatment, consult your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Ref:  U.S. National Library of Medicine.


This information is provided for reference only and not a replacement for and should only be used in conjunction with full consultation with a registered medical practitioner. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, mph-bd shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

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