P  - Caution when used during pregnancy

L  - Caution when used during lactation

Molecule Info

 
Indication & Dosage Topical/Cutaneous
Psoriasis, Seborrhoeic dermatitis
Adult: As lotion (containing betamethasone 0.05% w/w as dipropionate and salicylic acid 2% w/w) or ointment (containing betamethasone 0.05% w/w as dipropionate and salicylic acid 3% w/w): Apply to the affected area 1-2 times daily.
Overdosage Excessive prolonged use of topical corticosteroids can lead to pituitary-adrenal suppression resulting in secondary adrenal insufficiency. Excessive topical application of preparations containing salicylic acid may also result in symptoms of salicyclism. Treatment is symptomatic.
Contraindications Viral skin infections e.g. vaccinia, varicella and herpes simplex. Tuberculosis, acne rosacea, fungal skin infections (moniliasis), perioral dermatitis and ulcerative conditions.
Special Precautions Not to be used in or near the eyes. Avoid contact with mucous membranes. Prolonged topical corticosteroid treatment may result in systemic corticosteroid effects; may also lead to formation of striae or atrophy of the skin or subcutaneous tissue. Absorption of corticosteroid through the skin is increased when used with occlusive dressings. Caution when used in patients with stasis dermatitis or other skin diseases with impaired blood circulation. Treatment should be re-evaluated on a 4-wkly basis. Pregnancy and lactation.
Adverse Drug Reactions Pruritus, irritation, folliculitis, maceration of skin, skin atrophy, hypertrichosis, acneiform eruptions, secondary infection, hypopigmentation, perioral dermatitis, allergic contact dermatitis, striae and miliaria.
Storage Topical/Cutaneous: Lotion: Store <25°C. Ointment: Store <30°C.
Pharmacology Betamethasone dipropionate is a synthetic fluorinated corticosteroid. It is active topically and produces a rapid and sustained response in inflammatory dermatoses. It is also effective in less responsive conditions e.g. scalp psoriasis, chronic plaque psoriasis of the hands and feet. Salicylic acid has keratolytic action. It softens keratin, loosens cornified epithelium and desquamates the epidermis. It aids in the penetration of betamethasone.
Absorption: Betamethasone dipropionate: Percutaneous absorption depends on several factors e.g. use of occlusive dressings and integrity of the epidermal barrier. Salicylic acid: Exerts only local action after topical application.
Distribution: Betamethasone dipropionate: Once absorbed systemically, it is bound to plasma proteins in varying extents.
Metabolism: Betamethasone dipropionate: Once absorbed through the skin, it is metabolised mainly by the liver.
Excretion: Betamethasone dipropionate: Once absorbed through the skin, it is excreted largely renally; may also be excreted via the bile.
ATC Classification S01CB04 - betamethasone ; Belongs to the class of corticosteroids/antiinfectives/mydriatics combinations. Used in the treatment of eye diseases. 
D07AC01 - betamethasone ; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases. 
H02AB01 - betamethasone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations. 
S02BA07 - betamethasone ; Belongs to the class of corticosteroids used in the treatment of inflammation of the ear. 
A07EA04 - betamethasone ; Belongs to the class of corticosteroids acting locally. Used in the treatment of intestinal inflammation. 
R03BA04 - betamethasone ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticooids. 
S03BA03 - betamethasone ; Belongs to the class of corticosteroids used in ophthalmologic and otologic preparations. 
D01AE12 - salicylic acid ; Belongs to the class of other antifungals for topical use. Used in the treatment of fungal infection. 
C05AA05 - betamethasone ; Belongs to the class of products containing corticosteroids for topical use. Used in the treatment of hemorrhoids. 
D07XC01 - betamethasone ; Belongs to the class of potent (group III) corticosteroids in other combinations. Used in the treatment of dermatological diseases. 
R01AD06 - betamethasone ; Belongs to the class of topical corticosteroids used as nasal decongestants. 
S01BC08 - salicylic acid ; Belongs to the class of non-steroidal antiinflammatory agents. Used in the treatment of inflammation of the eye. 
S01BA06 - betamethasone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
 

Brand/Product Info


Total Products : 3   
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
Betamesal Scalp Incepta Pharmaceuticals Limited Betamethasone Dipropionate BP equivalent to 0.50mg of Betamethasone and Salicylic Acid BP 20mg per gm Lotion 30ml:MRP 150 Tk
DIPROSAL Aristopharma Ltd. Betamethasone dipropionate BP 0.05%+ Salicylic Acid BP 2% Lotion 30ml: 150.00 MRP
PROSALIC LOTION Square Pharmaceuticals Ltd. Betamethasone Dipropionate 0.05% + Salicylic Acid 2% Lotion 25 ml: 150.45 MRP