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PCaution when used during lactation : Caution when used during pregnancy

LCaution when used during lactation : Caution when used during lactation

Molecule Info

 | See TERMINOLOGY & ABBREVIATIONS |

Indication(s) & Dosage

Dyspeptic symptom complex that is often associated with delayed gastric emptying, gastro-oesophageal reflux and oesophagitis: Epigastric sense of fullness, early satiety, feeling of abdominal distension, upper abdominal pain;bloatingeructationflatulencenausea and vomiting; heartburn with or without regurgitation of gastric contents in the mouth.

Nausea and vomiting of functional, organic, infectious or dietetic origin or induced by radiotherapy or drug therapy. A specific indication is nausea and vomiting induced by dopamine agonists, as used in Parkinson's disease (eg, L-dopa and bromocriptine).

It is recommended to take oral Domperidone before meals. If taken after meals, absorption of the drug is somewhat delayed.

Oral route

Nausea and vomiting
Adult: 10-20 mg every 4-8 hr. Max: 80 mg/day.
Child: >2 yr and >35 kg: 10-20 mg 3-4 times daily. Max: 80 mg daily.

Infants and Children: 0.25-0.5 mg/kg 3-4 times/day with a maximum daily dose of 2.4 mg/kg (but do not exceed 80 mg/day). Suspension: 0.25-0.5 mg/kg 3-4 times/day with a maximum dose of 2.4 mg/kg (not exceeding 80 mL). 

Non ulcer dyspepsia
Adult: 10-20 mg tid and at night.

Migraine
Adult: 20 mg every 4 hr, in combination with paracetamol, as required. Max: 4 doses in 24 hr.

Per Rectal
Nausea and vomiting
Adult: 60 mg bid. 
Child: 60 mg bid. 
Special Populations: Use in children is restricted to nausea and vomiting following cytotoxics or radiotherapy.

Administration

Tab: Should be taken on an empty stomach. Take before meals.
Cap (if available): May be taken with or without food.

Contraindications

Hypersensitivity. GI haemorrhage, obstruction and perforation, patients with prolactin releasing pituitary hormone, chronic admin or routine prophylaxis of postoperative nausea and vomiting.

Special Precautions

Phaeochromocytoma; children<2 yr, elderly; renal or hepatic impairment. Risk of cardiac arrhythmias and hypokalaemia if administered IV. Pregnancy and lactation.

Adverse Drug Reaction(s)

Drowsiness, extrapyramidal reactions, galactorrhoea, gynaecomastia; constipation or diarrhoea, lassitude, decreased libido, skin rash, itch.
Potentially Fatal: Convulsions, arrhythmias and cardiac arrest, dysrrhythmias in patients with CV disease or hypokalaemia, patients on cancer chemotherapy. Seizures; hypertensive crisis in patients with phaeochromocytoma.

Drug Interactions

Reduces absorption of digoxin. Increases absorption of aspirin, paracetamol and oral diazepam. Enhances CNS depression by phenothiazine. Antimuscarinic agents and opioids antagonise GI effects. May antagonise hypoprolactinaemic effect of drugs such as bromocriptine. Increased effects when used with CYP3A4 inhibitors such as erythromycin or ritonavir.

Food Interaction

Delayed absorption but higher bioavailability due to reduced first-pass metabolism in gut wall.

Pregnancy Category (FDA)

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

In 2nd-3rd trimesters: Category D. There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

Storage

Oral: Store at 15-30°C. Rectal: Store at 15-30°C.

Pharmacology

Domperidone is a peripheral dopamine-receptor blocker, synthetic gastrokinetic and antinauseant.
Domperidone is a dopamine antagonist with antiemetic properties similar to those of metoclopramide and certain neuroleptic drugs. Unlike these other drugs, however, domperidone does not readily cross the blood-brain barrier. In domperidone users, especially adults, extrapyramidal side effects are very rare, but domperidone promotes the release of prolactin from the pituitary. Its antiemetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone, which lies outside the blood-brain barrier in the area postrema. Animal studies, together with low concentrations found in the brain, indicate a predominantly peripheral effect of domperidone on dopamine receptors.
Studies in man have shown oral domperidone to increase the duration of antral and duodenal contractions, to increase the gastric emptying of liquids and semi-solids in healthy subjects and of solids in patients in whom it was delayed, and to increase lower oesophageal sphincter pressure in healthy subjects. It has no effect on gastric secretion.
Pharmacokinetics: In fasting subjects, domperidone is rapidly absorbed after oral administration, with peak plasma concentrations at approximately 1 hr. The low absolute bioavailability of oral domperidone (approximately 15%) is due to an extensive first-pass metabolism in the gut and liver. Although domperidone's bioavailability is enhanced in normal subjects when taken after a meal, patients with gastrointestinal complaints should take domperidone 15-30 min before a meal. Reduced gastric acidity impairs the absorption of domperidone. Oral bioavailability is decreased by prior administration of cimetidine or sodium bicarbonate. The time of peak absorption is slightly delayed and the AUC somewhat increased when the oral drug is taken after a meal.
Oral domperidone does not appear to accumulate or to induce its own metabolism; a peak plasma level after 90 min of 21 ng/mL after 2 weeks oral administration of 30 mg/day was almost the same as that of 18 ng/mL after the 1st dose. Domperidone is 91-93% bound to plasma proteins. Distribution studies with radiolabelled drug in animals have shown wide tissue distribution but low brain concentrations. Small amounts of drug cross the placenta in rats. Domperidone concentrations in breast milk of lactating women are 4 times lower than corresponding plasma concentrations.
Domperidone undergoes rapid and extensive hepatic metabolism by hydroxylation and N-dealkylation. In vitro metabolism experiments with diagnostic inhibitors revealed that CYP3A4 is a major form of cytochrome P-450 involved in the N-dealkylation of domperidone, whereas CYP3A4, CYP1A2, CYP2W1 are involved in domperidone aromatic hydroxylation. Urinary and faecal excretions amount to 31 and 66% of the oral dose respectively. The proportion of the drug excreted unchanged is small (10% of faecal excretion and approximately 1% of urinary excretion).
The plasma half-life after a single oral dose is 7-9 hrs in healthy subjects but is prolonged in patients with severe renal insufficiency.

Domperidone increases oesophageal peristalsis, lower oesophageal sphincter pressure, gastric motility and peristalsis, thus facilitating gastric emptying and decreasing small bowel transit time.
Onset: Oral: 30 min-1hr.
Duration: Oral: 6-8 hr.
Absorption: Peak plasma concentrations after 1 hr (rectal), 30 min (oral).
Distribution: Enters breast milk (small amounts). Protein-binding: >90%.
Metabolism: Extensively hepatic.
Excretion: Urine (as metabolites), faeces (as unchanged drug); 7.5 hr (elimination half-life).

ATC Classification

A03FA03 - domperidone; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.

Brand/Product Info


Total Products : 171                                                                                                                                                                           
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
ADEGUT Supreme Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 75.00 MRP
ADEGUT Suspension Supreme Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
ADOREX Ambee Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 96.00 MRP
ADOREX Drop Ambee Pharmaceuticals Ltd. Domperidone 5mg/ml Drop 15mldrop : 20.07 MRP
ADOREX Suspension Ambee Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.10 & 38.14 MRP
ANET Kemiko Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
ANET Suspension Kemiko Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
APEDOM Apollo Pharmaceutical Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
APEDOM Suspension Apollo Pharmaceutical Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 27.00 IP
APULDON Aristopharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
APULDON Drop Aristopharma Ltd. Domperidone 5mg/ml Drop 15mldrop : 20.00 MRP
APULDON Suspension Aristopharma Ltd. Domperidone 5mg/5ml Suspension 60ml: 30.00 MRP
ATIDON Asiatic Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
ATIDON Suspension Asiatic Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
AVOMIT Chemist Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
AVOMIT Suspension Chemist Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
BERIDOM Belsen Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
BERIDOM Suspension Belsen Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
BPDON Bristol Pharma Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 100.00 MRP
COSY Orion Pharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
COSY Suspension Orion Pharma Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.10 & 38.14 MRP
CPDOM Cosmo Pharma Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DEDOM Decent Pharma Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 190.00 MRP
DEDOM Suspension Decent Pharma Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DEFLUX Beximco Pharmaceuticals Ltd Domperidone BP 10 mg Tablet 150's: 375.00 MRP
DEFLUX DROP Beximco Pharmaceuticals Ltd Domperidone 5mg/ml Paediatric Drop Drop 15ml: 20.00 MRP
DEFLUX DT Beximco Pharmaceuticals Ltd Domperidone BP 10 mg dispersible tablet Tablet (Dispersible) 100's: 200.00 MRP
DEFLUX SUSP Beximco Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 100ml: 38.00 MRP
DEGUT Delta Pharma Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DEGUT Suspension Delta Pharma Limited Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOMAR Pacific Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 190.00 MRP
DOMAR Suspension Pacific Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 25.00 & 40.00 MRP
DOMIDON Ziska Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMIDON Suspension Ziska Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOMILIN General Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
DOMILIN Suspension General Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 100ml: 40.15 MRP
DOMILUX Popular Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 200's: 301.91 MRP
DOMILUX Suspension Popular Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.12 MRP
DOMIN Opsonin Pharma Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMIN Drop Opsonin Pharma Limited Domperidone 5mg/ml Paediatric Drop 15mldrop: 20.00 MRP
DOMIN Suppository Opsonin Pharma Limited Domperidone 15mg & 30mg Suppository 15mg x 10's, 30mg x 10's: 50.00 & 80.00 MRP
DOMIN Suspension Opsonin Pharma Limited Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOMINAT Nipa Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMINAT Suspension Nipa Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 27.00 MRP
DOMINOL The White Horse Pharma Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMIREN Renata Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
DOMIREN Drop Renata Limited Domperidone 5mg/ml Paediatric Drop 15mldrop: 20.07 MRP
DOMIREN Suspension Renata Limited Domperidone 5mg/5ml Suspension 60ml: 28.10 MRP
DOMPA-S Seema Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMPA-S Suspension Seema Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOMPEN Millat Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMPI Alco Pharma Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DOMPI Suspension Alco Pharma Ltd Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOMSIL Silva Pharmaceuticals Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.75 MRP
DOMSIL DT Silva Pharmaceuticals Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet (dispersible) 100's: 200.75 MRP
DOMSIL Suspension Silva Pharmaceuticals Limited Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.10 & 38.14 MRP
DOMSTAL APC Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
DOMSTAL Suspension APC Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DON-A The Acme Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
DON-A Drop The Acme Laboratories Ltd. Domperidone 5mg/ml Drop 15mldrop: 20.07 MRP
DON-A Suppository The Acme Laboratories Ltd. Domperidone 15mg & 30mg Suppository 15mg x 10's, 30mg x 10's: 50.10 & 80.40 MRP
DON-A Suspension The Acme Laboratories Ltd. Domperidone 5mg/5ml Suspension 30ml, 60ml: 25.10 & 28.10 MRP
DOPADON IBN SINA Pharmaceutical Industry Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 225.00 MRP
DOPADON Suspension IBN SINA Pharmaceutical Industry Ltd. Domperidone 5mg/5ml Suspension 60ml: 30.00 MRP
DOPAGUT Concord Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
DOPAGUT Suspension Concord Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DOPON Shamsul Alamin Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 50.00 MRP
DORIDON Medicon Laboratories Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DORIDON Drop Medicon Laboratories Ltd Domperidone 5mg/ml Drop 15mldrop: 25.00 MRP
DP DONE Central Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
DP DONE Suspension Central Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
DUDON Kumudini Pharma Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
DUDON Suspension Kumudini Pharma Ltd Domperidone 5mg/5ml Suspension 60ml: 24.00 MRP
DYSNOV Unimed & Unihealth Manufacturers Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
DYSNOV Drop Unimed & Unihealth Manufacturers Ltd. Domperidone 5mg/ml Drop 15mldrop: 20.00 MRP
DYSNOV Suspension Unimed & Unihealth Manufacturers Ltd. Domperidone 5mg/5ml Suspension 100ml: 38.00 MRP
EDONE Zenith Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
EDONE Suspension Zenith Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.00 & 38.00 MRP
EGUT Euro Pharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
EGUT Suspension Euro Pharma Ltd. Domperidone 5mg/5ml Suspension 100ml: 28.00 MRP
EMEDON Cosmic Chemical Industries Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
EMIDOM Somatec Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
EMIDOM Drop Somatec Pharmaceuticals Ltd. Domperidone 5mg/ml Drop 15ml: 20.08 MRP
EMIDOM Suspension Somatec Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.11 & 38.00 MRP
ERIDON Doctors Chemical Works Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 100.00 MRP
ERIDON Suspension Doctors Chemical Works Ltd Domperidone 5mg/5ml Suspension 60ml: 25.00 MRP
ESOGUT Biopharma Laboratories Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
ESOGUT Drop Biopharma Laboratories Ltd Domperidone 5mg/ml Drop 15ml: 20.08 MRP
ESOGUT Suspension Biopharma Laboratories Ltd Domperidone 5mg/5ml Suspension 60ml: 28.11 MRP
EVDOM Everest Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
EVDOM Suspension Everest Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
GIDORA Rephco Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
GIDORA Suspension Rephco Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
GUTSET Ad-din pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 171.00 MRP
GUTSET Drop Ad-din pharmaceuticals Ltd. Domperidone 5mg/ml Drop 15ml: 18.28 MRP
I-PEDOM Indo-Bangla Pharmaceuticals Works Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
I-PEDOM Suspension Indo-Bangla Pharmaceuticals Works Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
LORIDON Modern Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
LORIDON Drop Modern Pharmaceuticals Ltd Domperidone 5mg/ml Drop 15ml: 20.00 MRP
LORIDON Suspension Modern Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
LOVAL Jayson Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
LOVAL Suspension Jayson Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.10 & 38.15 MRP
MERIN Edruc Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 IP
MERIN Suspension Edruc Limited Domperidone 5mg/5ml Suspension 100ml: 38.00 MRP
MOTIDOM Medimet Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 75.00 MRP
MOTIFAST Square Pharmaceuticals Ltd. Domperidone 10mg Orally Dispersible Tablet 10x10's: 251.00 MRP
MOTIGEN Novo Healthcare and Pharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 100.00 MRP
MOTIGUT Square Pharmaceuticals Ltd. Domperidone 10mg Tablet 15x10's: 376.5 MRP
MOTIGUT DROP Square Pharmaceuticals Ltd. Domperidone 5mg/ml Paediatric Drop 15ml: 25.00 MRP
MOTIGUT P-DROP Square Pharmaceuticals Ltd. Domperidone 5mg /ml Paediatric Drops 15 ml: 25.08 MRP
MOTIGUT SUSP Square Pharmaceuticals Ltd. Domperidone 5mg/5 ml Suspension 60 ml: 35.11 MRP
MOTILANT Marksman Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 100.00 MRP
MOTILANT Suspension Marksman Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 60ml: 27.00 MRP
MOTILEX Techno Drugs Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 75.00 MRP
MOTILEX Suspension Techno Drugs Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
MOTINORM Sharif Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
MOTIPER Mystic Pharmaceuticals Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
MOTIPER Suspension Mystic Pharmaceuticals Limited Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
MOTTL Hallmark Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
MOTTL Suspension Hallmark Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 100ml: 28.00 MRP
MYODON Peoples Pharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
MYODON Suspension Peoples Pharma Ltd. Domperidone 5mg/5ml Suspension 60ml: 20.00 MRP
NOBURN Beacon Pharmaceuticals Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
NORMOGUT Rangs Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
NORMOGUT Suspension Rangs Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 100ml: 38.00 MRP
OMID Desh Pharmaceuticals (Pvt) Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
OMID Suspension Desh Pharmaceuticals (Pvt) Ltd Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
Omidon Incepta Pharmaceuticals Limited Domperidone Maleate BP equivalent to 10mg Domperidone Film Coated Tablet 10x10's :MRP 200 Tk
Omidon 100ml Incepta Pharmaceuticals Limited Domperidone 5 mg/5ml Suspension 100ml :MRP 38 Tk
Omidon 60ml Incepta Pharmaceuticals Limited Domperidone 5 mg/5ml Suspension 60ml :MRP 28 Tk
Omidon D Incepta Pharmaceuticals Limited Domperidone BP 10 mg Dispersible Tablet 10x10's :MRP 200 Tk
Omidon Drop Incepta Pharmaceuticals Limited Domperidone 5 mg/ml Paediatric Drop Drop 15ml :MRP 20 Tk
P-DON Pharmadesh Laboratories Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
P-DON Suspension Pharmadesh Laboratories Limited Domperidone 5mg/5ml Suspension 60ml: 27.00 MRP
PARIDON Drug International Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
PARIDON Suspension Drug International Ltd Domperidone 5mg/5ml Suspension 100ml: 32.00 MRP
PERI Hudson Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
PERI Suspension Hudson Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 100ml: 35.00 MRP
PERIGUT S.N. Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
PERION Globe Pharmaceuticals Ltd Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
PERION Suspension Globe Pharmaceuticals Ltd Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.00 & 38.00 MRP
PROKENET NIPRO JMI Pharma Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
PROKENET Suspension NIPRO JMI Pharma Ltd. Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
PROTIX Apex Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 100.00 MRP
PROTIX Suspension Apex Pharmaceuticals Ltd. Domperidone 5mg/5ml Suspension 100ml: 25.00 MRP
REGUT Reliance Pharmaceuticals Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
REMADON Reman Drug Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 195.00 MRP
RIDON Eskayef Bangladesh Ltd Domperidone Maleate BP equivalent to 10mg Domperidone Tablet 100's MRP: 200.00
RIDON Drop Eskayef Bangladesh Ltd Domperidone 5mg/ml Paediatric Drop Drop 15ml MRP: 20.00
RIDON Eff. Granule Eskayef Bangladesh Ltd Domperidone BP 10mg Effervescent granules 20's MRP: 100.00
RIDON Suspension Eskayef Bangladesh Ltd Domperidone 5mg/5ml Suspension 60ml MRP: 28.00
SANDOM Sanofi Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 201.00 MRP
SANDOM Drop Sanofi Domperidone 5mg/ml Drop 15ml: 20.07 MRP
SANDOM Suspension Sanofi Domperidone 5mg/5ml Suspension 60ml: 28.10 MRP
SYDON Syntho Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
SYDON Suspension Syntho Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 27.00 MRP
VAVE ACI Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 150's: 300.00 MRP
VAVE Drop ACI Ltd. Domperidone 5mg/ml Drop 15ml: 20.07 MRP
VAVE OD ACI Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
VAVE Suspension ACI Ltd. Domperidone 5mg/5ml Suspension 60ml, 100ml: 28.11 MRP. 38.14 MRP
VEGADON Pharmasia Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 150.00 MRP
VEGADON Suspension Pharmasia Limited Domperidone 5mg/5ml Suspension 60ml: 28.10 MRP
VOMINO Monico Pharma Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP
VOMINO Suspension Monico Pharma Limited Domperidone 5mg/5ml Suspension 60ml: 28.00 MRP
VOMITOP Navana Pharmaceuticals Limited Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 120.00 MRP
VOMITOP Drop Navana Pharmaceuticals Limited Domperidone 5mg/ml Drop 15ml: 20.08 MRP
VOMITOP Suspension Navana Pharmaceuticals Limited Domperidone 5mg/5ml Suspension 60ml: 24.09 MRP
XEPADON Amico Laboratories Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 50's: 100.00 MRP
XEPADON Drop Amico Laboratories Ltd. Domperidone 5mg/ml Drop 15ml: 18.00 MRP
XEPADON Suspension Amico Laboratories Ltd. Domperidone 5mg/5ml Suspension 60ml: 25.00 MRP
XERIDON R A K Pharmaceuticals Pvt. Ltd. Domperidone Maleate BP equivalent to Domperidone 10mg Tablet 100's: 200.00 MRP

Gen. MedInfo

Why Domperidone is prescribed?

Domperidone helps to relieve nausea and vomiting. It also helps to reduce the symptoms of stomach wind and bloated stomach. Domperidone is also used to relieve reflux disease (also known as "heartburn", in which food or acid from your stomach backs up into your mouth, leaving a sour or bitter taste).

How should Domperidone be used?

Take Domperidone exactly as directed by your doctor. Do not take more or less than instructed by your doctor.

Take Domperidone on an empty stomach 15-30 minutes before meals.

Do not give Domperidone to children unless instructed by the doctor.

What to do if I have forgotten to take Domperidone?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule. 

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor know.

What special precautions to follow?

Alert your doctor if you have stomach problems (such as stomach bleeding or intestinal blockage) or prolactinoma (a tumour that releases a hormone called prolactin).

Alert your doctor if you have heart, liver or kidney disease, or if you have breast cancer.

Alert your doctor if you are pregnant or breastfeeding. Do not breastfeed while being treated with Domperidone.

What to take note of while taking Domperidone?

Let your doctor know if your stomach problems seem to be getting worse or if Domperidone does not seem to help.

What side effects could appear?

Side effects with Domperidone are not common, but may include headache and dry mouth.

Can I take this with other medicines?

Alert your doctor quickly if you are taking any of the following medications:

- bromocriptine
- heart medicines, especially those used to control irregular heartbeat
- antidepressants known as MAOI, such as phenelzine, isocarboxazid
- other mood medicines such as mesoridazine, thioridazine
- painkillers such as codeine, morphine

Always inform your doctor if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

What special dietary instructions to follow?

Avoid alcohol.

How to store Domperidone?

Store in a cool, dry place away from the reach of children. 
Medicines must not be used within the expiry date.

 

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