P  - Contraindicated in pregnancy

L  - Contraindicated in lactation

Molecule Info

 
Indication & Dosage Oral
Prophylaxis of migraine, Prophylaxis of vertigo and vestibular disorders, Prophylaxis of peripheral and cerebrovascular disorders
Adult: 5-10 mg daily at bedtime.
Administration May be taken with or without food.
Contraindications Pregnancy, lactation, GI or urinary tract obstruction, acute porphyrias.
Special Precautions Driving or operating machinery, epilepsy, elderly, CVS disease, glaucoma.
Adverse Drug Reactions Drowsiness. Rarely wt gain, headache, depression, gastric pain, dry mouth, insomnia, extrapyramidal reactions, galactorrhoea.
Drug Interactions Plasma levels reduced by phenytoin, carbamazepine, valproic acid. Please consult detailed drug interactions before prescribing.
Storage Oral: Store below 25°C.
Pharmacology Flunarizine has H1-receptor blocking action and calcium-channel blocking effect. It has also been used as an adjunct epileptic therapy for patients refractory to standard treatment regimens.
Absorption: Absorbed well from the GI tract (oral).
Distribution: Highly lipophilic. Protein-binding: >90%.
Metabolism: Extensive.
Excretion: Via bile (as metabolites); 18 days (elimination half-life).
ATC Classification N07CA03 - flunarizine ; Belongs to the class of preparations used in the treatment of vertigo.

Brand/Product Info


Total Products : 10          
Brand Name Manufacturer/Marketer Composition Dosage Form Pack Size & Price
FLUNARIN Apex Pharmaceuticals Ltd. Flunarizine 5mg & 10mg Tablet 5mg x50's, 10mg x30's: 100.00 & 90.00 MRP
FLURIUM 10 Beximco Pharmaceuticals Ltd Flunarizine Dihydrochloride BP eq. to Flunarizine 5mg Tablet 30's: 150.00 MRP
FLURIUM 5 Beximco Pharmaceuticals Ltd Flunarizine Dihydrochloride BP eq. to Flunarizine 5mg Tablet 30's: 90.00 MRP
FLURIZIN 10 Square Pharmaceuticals Ltd. Flunarizine 10mg Tablet 5x10's: 251.00 MRP
FLURIZIN 5 Square Pharmaceuticals Ltd. Flunarizine 5mg Tablet 5x10's: 175.50 MRP
FLUVER ACI Ltd. Flunarizine 5mg & 10mg Tablet 5mg x100's, 10mg x80's: 350.00 & 400.00 MRP
IMIGRA Navana Pharmaceuticals Limited Flunarizine 5mg & 10mg Tablet 5mg x50's, 10mg x30's: 150.00 & 120.60 MRP
MINIUM Opsonin Pharma Limited Flunarizine 5mg & 10mg Tablet 50's each: 150.00 & 200.00 MRP
NORIUM Eskayef Bangladesh Ltd Flunarizine hydrochloride INN equivalent to Flunarizine 5mg & 10mg Tablet 5mg x100's & 10mg x60's MRP: 350.00 & 300.00
RIZELIUM Unimed & Unihealth Manufacturers Ltd. Flunarizine 5mg & 10mg Tablet 30's each: 105.00 & 150.00 MRP