Antithrombotic anticoagulant therapy with warfarin is underutilized despite claer guideline documented indications because of the inherent risk of hemorrhage and the subsequent difficulties in utilization of warfarin therapy.

Read more: 

  1. Directions in Anticoagulation (2012) from The American Journal of Medicine.

  2. Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation. 

    Harrington ARArmstrong EPNolan PE JrMalone DC.  Stroke. 2013 Jun;44(6):1676-81. Epub 2013 Apr 2.